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精彩回顾:第 17 届国际抗磷脂抗体大会

六月 30, 2022 12:00 下午

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第 17 届 ICAPA(International Congress on Antiphospholipid Antibodies,国际抗磷脂抗体大会,以下简称 ICAPA)近日于阿根廷圆满闭幕。ICAPA 是三年一届的国际学术盛会,本次大会世界顶级专家汇聚一堂,从 APS 的分子学机制,标准与非标准抗磷脂抗体的机理、检测方法及临床应用,APS 与新型冠状肺炎等多个维度探讨了 APS 相关的临床及基础研究前沿问题。

沃芬荣幸邀请到意大利都灵大学 Savino Sciascia 教授,伦敦国王学院 Maria Laura Bertolaccini 教授和沃芬公司研发部 Carlos Ramirez 作为讲者,围绕“ APS 检测的新趋势与技术进展”为主题进行深入探讨。

两位教授从抗磷脂酰丝氨酸/凝血酶原抗体(aPS/PT)的分子机制开始,辅以多篇文献总结与临床案例,向大家深入浅出地分析了 aPS/PT 抗体检测对 APS 患者的临床意义。

Sciascia 教授重点介绍了:在标准抗体 (aCL, β2GPⅠ, LAC) 检测的基础上加入 aPS/PT 抗体的检测有助于 APS 的诊断,且在以下几个方面尤为重要:

1  对于携带抗磷脂抗体(aPL)但无症状的人群,aPS/PT 抗体检测可用于风险评估。

2  对于血清学阴性但临床高度怀疑 APS 的患者,aPS/PT 抗体检测可缩短血清学检测缺口。

3  在随访中标准 aPL 转阴的患者,aPS/PT 抗体检测可辅助临床诊疗。

4  aPS/PT 抗体检测可辅助临床进行治疗方案的选择 (例如:VKA Vs. DOAC)。

Bertolaccini 教授重点介绍了为什么我们需要定期对 APS 患者检测 aPS/PT 抗体,他在分享中提到 aPS/PT 抗体检测在临床上提高了 APS 的检出率,同时提出多项学术证据表明 aPS/PT 抗体可作为 APS 诊断与风险评估的指标 。

沃芬作为全球自身免疫领域的领导者,持续在众多自身免疫相关的国际学术会议上,如 ICAPA、ICA(International Congress on Autoimmunity,国际自身免疫大会)展示最新学术进展。沃芬将一如既往地致力于提高全球实验室医学质量,推动自身免疫检测技术发展,从而改善全球自身免疫疾病患者护理质量。重新定义自身免疫,我们一直在路上!

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